Varicella-zoster virus vaccine composition comprising cationic liposome and use thereof

摘要

The present invention relates to a varicella zoster virus vaccine composition comprising cationic liposomes and uses thereof, wherein lipopolysaccharide (LPS) analogues and cationic liposomes are novel structural immune response modulators with reduced toxicity. It relates to a varicella zoster virus vaccine composition comprising a and use thereof. The present invention overcomes the physicochemical instability of liposomes and is advantageous in production, transportation and storage, as well as improving stability and having advantages as an immune delivery system. In addition, the present invention includes both an immune response modulator and a cationic liposome, thereby exhibiting an enhanced immunopotentiating effect as compared to the case of using the immune response modifier alone. In addition, the present invention is all the components contained in the vaccine composition contained in one container can be prepared in a ready-to-use form is more convenient to use.