首页> 外国专利> A composition comprising chick bone marrow derived osteochondroprogenitor cell culture as an active ingredient for inducing differentiation of stem cells into chondrocytes

A composition comprising chick bone marrow derived osteochondroprogenitor cell culture as an active ingredient for inducing differentiation of stem cells into chondrocytes

机译:一种组合物,其包含鸡骨髓来源的骨软骨细胞原细胞培养物作为诱导干细胞分化成软骨细胞的活性成分

摘要

The present invention relates to a composition for inducing cartilage differentiation including chicken bone marrow-derived bone and cartilage progenitor cell culture medium as an active ingredient, and inferred chicken bone marrow-derived bone and cartilage progenitor cells have high proliferation ability and can be mass cultured. As a good bone and cartilage progenitor cell that secretly secretes various proteins that induce differentiation, the composition for inducing differentiation of stem cells into chondrocytes according to the present invention is an inferred chicken bone marrow in which secondary ossification center is not generated. It is possible to provide a low-cost, high-efficiency chondrocyte differentiation inducer using a culture medium of the derived bone and chondrocytes. Accordingly, the present invention relates to degenerative arthritis, rheumatoid arthritis, fractures, damage to muscle tissue, plantar fasciitis, humeral dermatitis, calcifying myositis, joint damage caused by non-union or trauma of fractures, etc. It is expected to be used as a health functional food for joint health as well as treatment and supplements.
机译:本发明涉及诱导软骨分化的组合物,其包含鸡骨髓来源的骨和软骨祖细胞培养基作为有效成分,并且推断鸡骨髓来源的骨和软骨祖细胞具有高增殖能力并且可以进行大规模培养。 。作为秘密分泌各种诱导分化的蛋白质的良好的骨软骨祖细胞,根据本发明的用于诱导干细胞分化为软骨细胞的组合物是不产生次生骨化中心的推断鸡骨髓。使用衍生的骨和软骨细胞的培养基可以提供低成本,高效率的软骨细胞分化诱导剂。因此,本发明涉及退行性关节炎,类风湿性关节炎,骨折,肌肉组织损伤,足底筋膜炎,肱骨性皮炎,钙化性肌炎,骨折不愈合或外伤引起的关节损伤等。预期将其用作用于关节健康以及治疗和补充的保健功能食品。

著录项

  • 公开/公告号KR102094733B1

    专利类型

  • 公开/公告日2020-03-30

    原文格式PDF

  • 申请/专利权人 서울대학교산학협력단;

    申请/专利号KR20170135444

  • 发明设计人 임정묵;안지연;

    申请日2017-10-18

  • 分类号C12N5/077;A23L33/10;A61K35/32;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:59

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