The present invention relates to α v β 3 integrin target single domain antibodies and various applications thereof. The α v β 3 integrin target single domain antibody of the present invention exhibits high binding ability, excellent tissue permeability, and bio stability to α v β 3 integrin associated with angiogenesis compared to conventional antibodies. In addition, the single domain antibody of the present invention can be easily measured in vitro, in vivo or ex vivo in combination with fluorescent particles, and is effective in detecting new blood vessels and diagnosing diseases related thereto, and thus can be usefully used in related industries. .
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机译：本发明涉及α v β 3 整联蛋白靶标单域抗体及其各种应用。本发明的α v β 3 整联蛋白靶单域抗体表现出高结合能力，优异的组织通透性和对α v 的生物稳定性。与常规抗体相比，β 3 整合素与血管生成有关。另外，本发明的单结构域抗体可以容易地在体外，体内或离体中与荧光颗粒组合测量，并且在检测新血管和诊断与之相关的疾病方面有效，因此可以有效地用于相关行业。 。
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