5--N-5S-2--3-4-56--4H-124-1--13--5--2- NOVEL CRYSTALLINE FORM OF 5-CHLORO-N-5S-2-OXO-3-4-56-DIHYDRO-4H-124TRIAZIN-1-YLPHENYL-13-OXAZOLIDIN-5-YLMETHYLTHIOPHENE-2-CARBOXAMIDE METHANESULFONATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

摘要

The present invention is 5-chloro-N-({(5S) -2-oxo-3- [4- (5,6-dihydro-4H- [1,2,4] triazin-1-yl) phenyl] A novel crystalline form of -1,3-oxazolidin-5-yl} methyl) thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition comprising the same, wherein the novel crystalline compound according to the present invention has high temperature and humidification. Since it exhibits excellent stability even in the environment, it can be useful for the prevention or treatment of diseases such as thrombosis, myocardial infarction, arteriosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.