nc886 A COMPOSITION FOR IMPROVING SKIN AGING AND SKIN INFLAMMATION COMPRISING EXPRESSION STIMULATORS OF NON-TRANSLATED GENE nc886 AND A METHOD SCREENING THE SAME

摘要

The present invention comprises a base sequence of SEQ ID NO: 1 or a non-translated gene nc886 expression accelerator represented by a base sequence having 90% or more homology to the composition for improving skin aging and skin inflammation, characterized in that it comprises Relates to a method for screening the expression promoter of the non-translated gene nc886 to improve the skin aging and skin inflammation, according to the present invention, skin aging by reducing the collagenase and COX-2 expression through over-expression of the non-translated gene nc886 And skin conditions such as skin inflammation. In addition, according to the present invention, by using a screening method of a material having an activity to improve skin aging and skin inflammation, which includes cells expressing the non-translated gene nc886, the aging of the skin is rapidly and efficiently confirmed by checking the expression level of the non-translated gene nc886. It is possible to screen a substance having an activity for improving skin inflammation.