pharmaceutical composition for the prevention or treatment of liver disease comprising a gomisine derivative as an active ingredient

摘要

The present invention relates to a pharmaceutical composition for preventing or treating liver disease comprising a hypermycin derivative as an active ingredient, the hypermycin derivative according to the present invention inhibits differentiation of hepatic stellate cells, and is a protein of type 1 A1 collagen fiber It has an effect of reducing accumulation and suppressing mRNA expression of α-SMA and collagen genes, and thus may be useful as a pharmaceutical composition for preventing or treating liver disease.