首页> 外国专利> COMPOSITION FOR PROMOTING DIFFERENTIATION OF AND PROTECTING NEURAL STEM CELLS AND METHOD FOR INDUCING NEURAL REGENERATION USING SAME

COMPOSITION FOR PROMOTING DIFFERENTIATION OF AND PROTECTING NEURAL STEM CELLS AND METHOD FOR INDUCING NEURAL REGENERATION USING SAME

机译:促进神经干细胞分化和保护的组合物以及使用相同方法诱导神经再生的方法

摘要

The present invention relates to a method of inducing nerve regeneration, comprising administering a MEK 1/2 inhibitor to a patient in need of regeneration. In particular, the MEK 1/2 inhibitor in the method of the present invention differentiates neural stem cells into nerve cells, protects nerve cells and neural stem cells from cytotoxicity by beta amyloid, or induces nerve regeneration by both. The present invention also relates to a method of protecting a neuron from loss or damage of the neuron, comprising administering a MEK 1/2 inhibitor. In addition, the present invention comprises administering the MEK 1/2 inhibitor to a patient in need of prevention or treatment of neurodegenerative diseases caused by loss or damage of nerve cells, nerves caused by loss or damage of nerve cells It relates to a method for preventing or treating degenerative diseases.
机译:本发明涉及一种诱导神经再生的方法,该方法包括向需要再生的患者施用MEK 1/2抑制剂。特别地,本发明方法中的MEK 1/2抑制剂将神经干细胞分化为神经细胞,保护神经细胞和神经干细胞免受β淀粉样蛋白的细胞毒性作用,或通过两者诱导神经再生。本发明还涉及保护神经元免受神经元丧失或损害的方法,该方法包括施用MEK 1/2抑制剂。另外,本发明包括向需要预防或治疗由神经细胞的丧失或损伤引起的神经退行性疾病,由神经细胞的丧失或损伤引起的神经的患者施用MEK 1/2抑制剂。预防或治疗退行性疾病。

著录项

  • 公开/公告号KR102114017B1

    专利类型

  • 公开/公告日2020-05-22

    原文格式PDF

  • 申请/专利权人 주식회사 지뉴브;

    申请/专利号KR20187017867

  • 发明设计人 김미연;한성호;

    申请日2017-11-23

  • 分类号G01N33/50;A61K31/519;C12N5/0793;G01N33/483;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:37

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