Attenuated adeno virus expressing Mycobacterium tuberculosis multivalent antigen and vaccine for preventing Mycobacterium tuberculosis comprising the same

摘要

The present invention is a recombinant adenovirus line comprising a multivalent antigen gene comprising Ag85B, ESAT6, MPT64, Rv2660 and a gene of the secretory signal peptide tPA, a vaccine/booster composition for preventing tuberculosis comprising the same, and a method of manufacturing the adenovirus line It is about.