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3 Injectable three-dimensional nano fiber scaffolds and method for preparing the same

机译:3可注射的三维纳米纤维支架及其制备方法

摘要

The present invention relates to an injectable three-dimensional nanofiber scaffold and a method for manufacturing the same. Injectable 3D nanofiber scaffolds according to the present invention, by coating a hydrogel on 3D electrospun biodegradable polymer nanofibers, grow cells in 3D, and at the same time, desire it in vivo through simple injection It was made possible to deliver to the site. In addition, in the process of delivering cells or drugs using the scaffold, it was confirmed that the cell proliferation activity could be maintained high while minimizing the detachment of cells by injection, and the drug release rate could be effectively controlled according to the hydrogel component. Bar, the present invention may be used as a core technology in the field of cell or drug treatment.
机译:可注射的三维纳米纤维支架及其制造方法技术领域本发明涉及一种可注射的三维纳米纤维支架及其制造方法。根据本发明的可注射3D纳米纤维支架,通过将水凝胶涂覆在3D电纺生物可降解聚合物纳米纤维上,使细胞在3D中生长,并且同时希望通过简单的注射在体内活体递送到该部位。另外,证实了在使用支架递送细胞或药物的过程中,可以维持高细胞增殖活性,同时通过注射使细胞的脱离最小化,并且可以根据水凝胶成分有效地控制药物释放速率。 。棒,本发明可用作细胞或药物治疗领域的核心技术。

著录项

  • 公开/公告号KR102135641B1

    专利类型

  • 公开/公告日2020-07-20

    原文格式PDF

  • 申请/专利权人 연세대학교 산학협력단;

    申请/专利号KR20200058351

  • 发明设计人 장재형;박국인;이슬기림;

    申请日2020-05-15

  • 分类号A61L27/56;A61K47/30;A61K9;A61L27/18;A61L27/52;A61L27/58;B82Y5;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:12

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