Orally Disintegrating Tablet comprising sugar or sugar alcohol granules reformed with ethyl cellulose

摘要

The present invention relates to an oral disintegrating tablet comprising as a house excipient sugar or sugar alcohol granules that have been wet-assembled with an ethyl cellulose solution and surface-modified, and a granular main excipient in which sugar or sugar alcohol is surface-modified with an ethyl cellulose solution is applied. As a result, high hardness can be obtained even with low pressure tableting, and practical production application is possible without tableting obstacles, it does not collapse during handling during manufacturing, transportation, storage, distribution, and preparation work, and hardness decreases even after long-term storage under high humidity conditions. It is possible to obtain an excellent oral disintegrating tablet capable of suppressing the delay of disintegration.