- E E METHOD FOR GENERATING HIGH-TITER HEPATITIS E VIRUS STOCKS AND TITRATION ASSAY FOR HEPATITIS E VIRUS

摘要

The present invention relates to a method for generating a hepatitis E virus stock and a method for titrating hepatitis E virus. The present invention is to provide the use of polybrene as an additive in the cell culture medium used in the method of high-titration and generation of hepatitis E virus stocks and used in the hepatitis E virus titration assay. In addition, it is to provide a cell culture medium containing polybrene, a method for confirming the presence and/or level of HEV in a sample, and a HEV titration measurement method using polybrene for high-titration HEV generation.