首页> 外国专利> Bromelain enzyme treated silkworm segment extracts having excellent vasorelaxant effect and anti inflammatory effect and use thereof

Bromelain enzyme treated silkworm segment extracts having excellent vasorelaxant effect and anti inflammatory effect and use thereof

机译:菠萝蛋白酶酶处理的蚕段提取物具有优异的血管松弛作用和抗炎作用及其用途

摘要

The present invention relates to a bromelain enzyme decomposition product derived from a cocoon having excellent vascular relaxation and anti-inflammatory activity, and to a use thereof, and specifically, the present invention comprises the steps of: adding sodium hydroxide solution to the cocoon and ultrasonicating to obtain an ultrasonic extract; And a method for producing a bromelain enzyme decomposition product of a cocoon having vascular inflammation inhibiting or vascular relaxation activity, comprising the step of hydrolyzing by adding bromelain enzyme to the ultrasonic extract, prepared by the above method A health functional food for preventing or improving vascular disease, a pharmaceutical composition for preventing or treating vascular disease, and a vascular relaxant composition containing bromelain enzyme decomposition product for the ultrasonic extract of cocoon as an active ingredient will be.
机译:本发明涉及衍生自具有优异血管舒张和抗炎活性的茧的菠萝蛋白酶分解产物及其用途,具体地,本发明包括以下步骤:向该茧中加入氢氧化钠溶液并超声处理获得超声波提取物;以及一种具有抑制血管炎症或血管松弛活性的茧的菠萝蛋白酶分解产物的制备方法,其包括通过将菠萝蛋白酶酶添加到超声提取物中而进行水解的步骤,所述水解物是通过上述方法制备的。疾病,用于预防或治疗血管疾病的药物组合物,以及包含用于蚕茧的超声波提取物的菠萝蛋白酶分解产物作为活性成分的血管松弛剂组合物。

著录项

  • 公开/公告号KR102161454B1

    专利类型

  • 公开/公告日2020-10-06

    原文格式PDF

  • 申请/专利权人 한국식품연구원;

    申请/专利号KR20190064628

  • 发明设计人 송경모;엄수진;이남혁;임태규;

    申请日2019-05-31

  • 分类号A61K35/64;A23L29;A23L33/18;A61K38/01;A61P9;A61P9/10;A61P9/12;

  • 国家 KR

  • 入库时间 2022-08-21 11:03:41

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