The present invention relates to an apparatus and method for producing dispersions and solids by controlled precipitation, coprecipitation and self-organization processes in a microjet reactor, wherein the jet of a solvent (2) comprising at least one target molecule is At the impact point (K) of the reactor chamber of the reactor collides with the jet of non-solvent (3) at a prescribed pressure and flow rate, and the microjet reactor has a gas inlet (5) and gas for introducing gas into the reactor chamber (1) It has a reactant outlet 6 for discharging the reactants into a stream of. This leads to very rapid precipitation, coprecipitation or chemical reactions in which microparticles or nanoparticles are produced. In order to provide an apparatus capable of performing solvent/non-solvent precipitation to produce as small particles as possible and not significantly affected by Ostwald ripening in the resulting dispersion, the present invention provides a spray-drying unit 7 at the outlet of the reactant. It is proposed to provide a control circuit 11 to connect and optimize and maintain the operating parameters of the spray-drying unit 7.
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机译: (54)标题:具有硅酸盐涂层的固体颗粒(54):FESTKoRPERPARTKEL MIT SILKATBESCHICHTUNG(57)摘要:本发明涉及一种具有二氧化硅涂层的固体颗粒的生产方法,其包括以下步骤:将固体颗粒分散为将其涂覆在水性介质中以产生固体颗粒分散体,通过缓冲系统调节固体颗粒分散体的pH以产生缓冲的固体颗粒分散体,并向缓冲的固体颗粒分散体中添加碱性硅酸盐溶液以形成二氧化硅在涂覆期间将其涂覆在固体颗粒上,其中选择缓冲体系和碱性硅酸盐溶液的量,使得在添加碱性硅酸盐溶液之前和在添加完成之后,缓冲的固体颗粒分散体的pH至少为7.0。碱性硅酸盐溶液的最大含量为11.0。固体颗粒优选是无机固体,特别是