3 assigning "0 points", in the presence of X3 – "1 point"; X2 – in absolute values, g/l; based on obtained data determining probability of adverse outcome of PAH SCTD (p) by formula: p=0.1624×exp(1.4103×X1+0.0365×X2+1.0636×X3), if p0.5, a low risk of an unfavorable outcome is stated if 0.5≤p0.7, the average risk of an unfavorable outcome is determined, in the cases p≥0.7, high risk of adverse outcome of PAH associated with SCTD.;EFFECT: method enables higher diagnostic accuracy.;1 cl, 2 ex"/> METHOD FOR RAPID ASSESSMENT OF THE RISK OF LETHAL OUTCOME IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH SYSTEMIC CONNECTIVE TISSUE DISEASES
首页> 外国专利> METHOD FOR RAPID ASSESSMENT OF THE RISK OF LETHAL OUTCOME IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH SYSTEMIC CONNECTIVE TISSUE DISEASES

METHOD FOR RAPID ASSESSMENT OF THE RISK OF LETHAL OUTCOME IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH SYSTEMIC CONNECTIVE TISSUE DISEASES

机译:快速评估系统性结缔组织疾病相关性肺动脉高压患者的结局风险

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, and aims at assessing the probability of an unfavorable outcome in the patients suffering pulmonary arterial hypertension (PAH) associated with systemic connective tissue diseases (SCTD). A uric acid level (X1), concentration of C-reactive protein (X2) and presence of anticentromere antibodies (X3); wherein X1 and X3 is evaluated in points, namely: with value X1≥435 mcmole/l, assigning "1 point", with value of 435 mcmole/l, assigning "0 points", in the absence of X3 assigning "0 points", in the presence of X3 – "1 point"; X2 – in absolute values, g/l; based on obtained data determining probability of adverse outcome of PAH SCTD (p) by formula: p=0.1624×exp(1.4103×X1+0.0365×X2+1.0636×X3), if p0.5, a low risk of an unfavorable outcome is stated if 0.5≤p0.7, the average risk of an unfavorable outcome is determined, in the cases p≥0.7, high risk of adverse outcome of PAH associated with SCTD.;EFFECT: method enables higher diagnostic accuracy.;1 cl, 2 ex
机译:技术领域本发明涉及医学,其目的在于评估患有与系统性结缔组织疾病(SCTD)相关的肺动脉高压(PAH)的患者中不利结果的可能性。尿酸水平(X 1 ),C反应蛋白浓度(X 2 )和抗着丝粒抗体(X 3 )的存在;其中X 1 和X 3 以点进行评估,即:值X 1 ≥435mcmole / l,分配“ 1点”,值<435 mcmole / l,在没有X 3 的情况下分配“ 0分”,在X 3 的情况下分配“ 0分” –“ 1点”; X 2 –绝对值,g / l;根据获得的数据确定PAH SCTD的不良结局概率(p),公式为:p = 0.1624×exp(1.4103×X 1 + 0.0365×X 2 + 1.0636× X 3 ),如果p <0.5,则表示不良结果的低风险,如果0.5≤p<0.7,则确定不良结果的平均风险,在p≥0.7的情况下,高与SCTD相关的PAH不良后果的风险。;效果:该方法可提高诊断的准确性。; 1 cl,2 ex

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