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COMBINATION THERAPY FOR TREATING CANCER WITH POXVIRUS EXPRESSING TUMOUR ANTIGEN AND ANTAGONIST AND/OR AGONIST OF IMMUNE CHECKPOINT INHIBITOR
COMBINATION THERAPY FOR TREATING CANCER WITH POXVIRUS EXPRESSING TUMOUR ANTIGEN AND ANTAGONIST AND/OR AGONIST OF IMMUNE CHECKPOINT INHIBITOR
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机译：联合表达肿瘤抗原的痘病毒和免疫检查点抑制剂的拮抗剂和/或激动剂治疗癌症的联合治疗
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摘要
FIELD: medicine.;SUBSTANCE: proposed group of inventions relates to medicine. Disclosed is a therapeutic agent for treating a human having cancer containing recombinant orthopoxvirus MVA-BN and an antagonist of anti-PD-1, which is an antibody. Disclosed is a method of treating a human having cancer, comprising administering to a patient a recombinant orthopoxvirus MVA-BN and said antagonist.;EFFECT: proposed group of inventions provides a synergetic effect associated with recombinant orthopoxvirus and antagonist anti-PD-1.;22 cl, 23 dwg, 24 ex
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机译：技术领域：药物：拟议的发明组涉及药物。公开了一种用于治疗患有癌症的人的治疗剂，所述人含有重组正痘病毒MVA-BN和作为抗体的抗PD-1拮抗剂。公开了一种治疗患有癌症的人的方法，其包括向患者施用重组正痘病毒MVA-BN和所述拮抗剂。效果：提出的一组发明提供了与重组正痘病毒和拮抗剂抗PD-1相关的协同作用。 22 cl，23 dwg，24 ex
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