NOVEL AZETIDINE DERIVATIVES, USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to organic chemistry, specifically to novel heterocyclic compounds of formula I or to their isomers or pharmaceutically acceptable salts, where R⁴ is F, R⁵ is H or C₁-C₄ alkyl substituted with 0 F, and n is 0, 1, 2 or 3. Also described is a pharmaceutical composition based on the compound of formula I and use of the compound of formula I as a monoamine level modulator. ; formula I.;EFFECT: technical result is obtaining novel 3-benzyl-azetidine derivatives, useful for modulation of monoamine levels.;15 cl, 32 ex, 4 tbl