;(I);and crystalline forms thereof (I) and (II), wherein said crystalline forms have characteristic peaks expressed in degrees 2θ(±0.2 2θ), at 21.563, 21.156, 23.295, 21.955 and 20.838 on an X-ray powder diffraction pattern obtained with radiation of Cu-Kα for form (I) and at 3.274, 21.481, 23.887 for form (II).;EFFECT: said rotigotine behenate is characterized by the ability to maintain its effective concentration in plasma for a long period of time, has high bioavailability and can provide the effect of prolonged, effective and stable release.;19 cl, 10 dwg, 6 tbl, 9 ex"/>
公开/公告号RU2717542C1
专利类型
公开/公告日2020-03-24
原文格式PDF
申请/专利号RU20180146096
发明设计人 YAN MINA (CN);TSZYAN YUNTAO (CN);MEN IN (CN);VAN TAO (CN);SYUJ TSYAN TSYAN (CN);SHAO SIN (CN);SHA CHUNTSZE (CN);
申请日2016-07-21
分类号C07D333/10;A61K31/381;A61P25/16;
国家 RU
入库时间 2022-08-21 11:02:33