COMPOSITIONS AND METHODS OF TREATING PARANASAL SINUS AND PARASITIC NASAL MUCOSA DISEASES WITH NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: described are methods of treating and preventing conditions of nasal mucosa or paranasal sinuses. Methods involve administering a pharmaceutical composition comprising a nicotinic acetylcholine receptor agonist (nAChR), for example, (S)-(1-methyl-2-pyrrolidinyl)-pyridine or a pharmaceutically acceptable salt thereof, an analogue, a precursor or a derivative thereof.;EFFECT: methods can be used for treating a wide range of conditions of the nasal mucous membrane or paranasal sinuses, for example, nasal congestion and epistaxis.;18 cl, 2 ex