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METHOD OF TUMOUR CELLS RADIOSENSITIZATION

机译:肿瘤细胞放射增敏的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to molecular biology and can be used to increase efficiency and targeted selectivity of effect on tumour cells using radiation exposure. Method for radiosensitization of tumour cells involves exposing a tumour cell to a substance which is a glycolysis inhibitor and simultaneously blocks cell proliferation, which is represented by glucosamine D hydrochloride in concentration of 10 mM.;EFFECT: invention provides higher radiosensitization and targeted selectivity of tumour cell exposure without affecting non-tumour cells by blocking cell proliferation in the radio-sensitive G1 phase of the cell cycle.;1 cl, 5 dwg
机译:技术领域本发明涉及分子生物学,并且可以用于提高使用放射线照射对肿瘤细胞的作用的效率和靶向选择性。肿瘤细胞放射增敏的方法包括将肿瘤细胞暴露于一种糖酵解抑制剂并同时阻断细胞增殖的物质,其以浓度为10 mM的葡萄糖胺D盐酸盐为代表。效果:本发明提供了更高的放射增敏性和靶向肿瘤的选择性通过在细胞周期的放射敏感性G1期阻止细胞增殖来暴露细胞而不影响非肿瘤细胞; 1 cl,5 dwg

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