METHOD FOR INITIATION OF TUMOUR CELL DEATH BY SODIUM SALT OF HEMATOPORPHYRIN, SUCCINIC ACID AND HF- AND MICROWAVE RADIATION WAVE ENERGY

摘要

FIELD: medicine.;SUBSTANCE: invention relates to a method for initiation of tumour cell death, intended for complex treatment of oncological patients having tumour tissues in all organs of human body, by hyperthermia HF- and UHF energy, characterized by that person for 3 days is transferred to a non-carbohydrate diet, to create glucose starvation and subsequent maximum saturation of tumour cells with an electron-ion solution of the sodium salt of hematoporphyrin Photogem preparation intravenously in megadose 3.1 mg/kg of human body weight and oral administration of succinic acid in disposable megadose 3000 mg per person, and after 72 hours after taking Photogam and succinic acid for 2.5 hours with maximum accumulation of preparations in tumour tissues is 8–10 times higher than in healthy, selective hyperthermia of tumour tissues is carried out with high-frequency energy in accordance with depth of their location and penetration depth of electromagnetic waves into a human body of 1100 cm, at the resolved frequency f = 13.56 MHz, with heating rate of tumour tissues 0.81 °C/s, for 190 s to temperature of tumour tissues 52 °C, while heating healthy tissues not higher than 40 °C.;EFFECT: said method results in thermal death of tumour tissues due to high dielectric contrast of the tumour and increasing difference in its conductivity (dielectric loss) relative to surrounding healthy biological tissues, which reaches multiple values for various tumours.;1 cl, 2 tbl