SUPPOSITORIES FOR TREATMENT OF MODERATE AND HIGH-INTENSITY PAIN SYNDROME

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine and chemical-pharmaceutical industry, namely to suppositories for treating moderate and high-intensity pain syndrome. Pharmaceutical composition of the rectal suppository contains 0.1–10 g/100 g of nefopam or its pharmaceutically acceptable salt, from 90 to 100 % of particles of which have size from 0.5 to 90 mcm, and up to 100 g/100 g of a lipophilic base with addition of parabens, sodium benzoate, emulsifier and stabilizer.;EFFECT: invention provides prolonging the analgesic effect and improving retention of the active substance.;6 cl, 4 tbl, 5 ex