PANAXDIOL-TYPE GINSENOSIDE DERIVATIVE, METHOD FOR PRODUCTION AND USE THEREOF

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to a panxediol-type ginsenoside derivative having a structure presented in formula I or formula II. In formula I and formula II, R₁ is , where R₃ is methyl; R₂ has the structure presented in formula III: formula III; in formula III n = 0, 1 or 2, R₄ is methyl or ethyl, R₅ is one of hydrogen atom, unsubstituted C3-C4 alkyl, unsubstituted benzyl, C1-C2 hydroxyalkyl, -CH₂CH₂COOCH₃, -CH₂COOCH₂CH₃, hydroxybenzyl, -CH₂-(1H-imidazol-4-yl) and -CH₂-(1H-indol-3-yl). Invention also relates to a method of producing and using a panaxdiol-type ginsenoside derivative.; ; ;EFFECT: technical result is obtaining novel derivatives of panaxdiol-type ginsenoside, having a structure of formula I or formula II, which can be used to produce a drug for preventing and treating atherosclerosis.;8 cl, 5 tbl, 33 ex