PH 7 INJECTION SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN WHICH PI IS BETWEEN 5.8 AND 8.5 AND AN AMPHIPHILIC COMPOUND CARRYING HYDROPHOBIC RADICALS

摘要

The invention relates to a composition which is physically stable in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, comprising at least: - a basal insulin whose isoelectric point (pI) is between 5.8 and 8.5, and - an amphiphilic compound comprising a hydrophilic backbone HB, substituted by at least one hydrophobic radical -Hy of formula I, - and a cation salt at least divalent.