The present invention relates to compounds of formula (I): in which R1 represents a group -NH2, -NHCORa, -NHCOORb, - (C2-C6) alkenylene-CO -NH-OH, - (C2-C6) alkynylene-CO -NH-OH or -OH; R2 represents a group -OCH3, -OCH2CH3, -SCH3, -SCH2CH3 or -OCHF2; R3 represents a hydrogen atom or a group -CH3, -CN, -F, -Cl or -ORc; R4 represents a hydrogen atom or a group -CH3, -CN, -F, -Cl or -ORd; Ra represents a hydrogen atom or a - (C1-C5) alkyl or -CF3 group; Rb represents a hydrogen atom or a - (C1-C5) alkyl or -CF3 group; Rc represents a group - (C1-C5) alkyl; and Rd represents a group - (C1-C5) alkyl or -CF3; in the form of a base or of acid or of salts of acids or of bases or in the form of a hydrate or of a solvate, and its isomeric forms. It also relates to antibody-drug conjugates comprising such compounds.
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