METHOD AND SYSTEM FOR SPECTRAL ANALYSIS AND DETERMINATION OF A MARKER FOR PROVIDING THE SAFETY OF THERAPEUTIC ULTRASOUND INTERVENTIONS

摘要

A process of spectral analysis and determination of a safety marker comprises a set by which: - regularly during the firing Bb at a series of instants ta, the temporal evolution of the spectral lines corresponding to the subharmonic and ultra-frequencies harmonics of an acoustic response signal of the microbubbles received is measured (106, 108), and the time evolution over the instants ta of a safety marker is determined and quantified (110, 112), the safety marker being defined at each instant ta by a number MDDa equal to the ratio of the sum of the areas of the spectral lines, measured at time ta and corresponding to the subharmonic and / or ultra-harmonic frequencies of the received signal of acoustic response of the microbubbles, on the sum of the spectral line areas, measured at the first instant t1 and corresponding to the subharmonic and / or ultra-harmonic frequencies of the acoustic response signal of the microbubbles. A system for spectral analysis and determination of a security marker implements said method.