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Microfluidic chips for particle purification and fractionation

机译:用于颗粒纯化和分级分离的微流控芯片

摘要

Microfluid chips that comprise one or more microscale and/or mesoscale condenser arrays, which can facilitate particle purification and/or fractionation, are described herein. In one embodiment, an apparatus can comprise a layer of a microfluidic chip. The layer can comprise an inlet that can receive fluid,an outlet that can output a purified version of the fluid, and a condenser array coupled between and in fluid communication with the inlet and the outlet. The condenser array can comprise a plurality of pillars arranged in a plurality of columns. Also, a pillar gap sized to facilitate a throughput rate of the fluid of greater than or equal to about 1.0 nanoliter per hour can be located between a first pillar of the plurality of pillars in a first column of the plurality of columns and a second pillar of the plurality of pillars in the first column.
机译:本文描述了包括一个或多个可以促进颗粒纯化和/或分级分离的微尺度和/或中尺度冷凝器阵列的微流体芯片。在一个实施例中,一种设备可以包括微流体芯片层。该层可以包括可以接收流体的入口,可以输出流体的纯化形式的出口,以及联接在入口和出口之间并与之流体连通的冷凝器阵列。冷凝器阵列可包括布置成多列的多个支柱。而且,可将尺寸适于促进流体的通过量每小时大于或等于约1.0纳升/小时的支柱间隙设置在多个支柱的第一支柱中的多个支柱的第一支柱和第二支柱之间。第一列中的多个支柱中的一个。

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