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The use of 2-carboxamidocycloaminourea derivatives in the treatment of acquired resistance to drugs that target EGFR dependent or EGFR family members
The use of 2-carboxamidocycloaminourea derivatives in the treatment of acquired resistance to drugs that target EGFR dependent or EGFR family members
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摘要
Problem to be solved: to provide an epidermal growth factor receptor (EGFR) dependent disease, or a method of treating a disease with acquired resistance to drugs targeting EGFR family members.Use of the compound of formula (I) for the manufacture of a pharmaceutical composition for the treatment and treatment of the disease.In the equation, a represents a particular heteroaryl; R1 and R3 represent certain substituents, and R2 represents hydrogen. ]No selection
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