A multi-layered hydrogel-nanofiber hybrid patch with improved mechanical property comprising marine resources extract

摘要

The present invention relates to a method for producing a hydrogel-nanofiber hybrid patch and a hydrogel-nanofiber hybrid patch prepared therefrom, more specifically (a) alginate, fucoidan, glycosaminoglycan, persimmon extract, crosslinking agent And preparing a hydrogel solution comprising a solvent; (b) preparing a hydrophobic polymer solution; (c) preparing a hydrogel from the hydrogel solution; And (d) electrospinning the hydrophobic polymer solution on the surface of the hydrogel to introduce nanofibers; a method for producing a hydrogel-nanofiber hybrid patch and a hydrogel-nanofiber hybrid patch prepared therefrom. It is about. The present invention can provide a method for producing a hydrogel-nano fiber hybrid patch having excellent moisturizing, wetting, anti-allergic, and antioxidant properties using marine resource extracts, and excellent mechanical properties and elasticity using nanofibers. have. In addition, the present invention can provide a hydrogel-nanofiber hybrid patch effective in alleviating symptoms of atopy (especially atopic dermatitis), which can be manufactured with a thin thickness and prevent lifting when attached to joints. You can.