Kits or packages for identifying pregnant women at risk of preterm birth and use of such kits or packages

摘要

A method, composition and kit for determining whether a pregnant woman is at risk of preterm birth. The method entail measuring the protein expression levels of Activin A, Adam12 and sFlt1 and their upregulation indicates that the woman is at risk of preterm risk. The prognosis can be made for women at different stages of pregnancy, including from 16 weeks to 27 weeks. Once a woman is prognosed to be at risk, suitable treatment procedure can be applied to mitigate the risk.