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NS1 protein of yellow fever virus, monoclonal antibody specifically binding thereto, and uses thereof

机译:黄热病病毒的NS1蛋白,与其特异性结合的单克隆抗体及其用途

摘要

The present invention relates to a recombinant NS1 protein derived from yellow fever virus, a monoclonal antibody specifically binding thereto, and the use thereof. The recombinant NS1 protein of the present invention can measure antibodies in a specific sample with high sensitivity and accuracy. In addition, the kit of the present invention, including the protein and the antibody specifically binding thereto, can be quickly and easily detected by dividing the antibody against yellow fever virus in the sample into IgM or IgG, and thus, when the yellow fever virus is infected, the vaccine It can be widely used to confirm the success or failure of inoculation.
机译:本发明涉及源自黄热病病毒的重组NS1蛋白,与其特异性结合的单克隆抗体及其用途。本发明的重组NS1蛋白可以高灵敏度和准确度地测量特定样品中的抗体。另外,通过将样品中的抗黄热病病毒的抗体分为IgM或IgG,并由此将黄热病病毒分离,可以快速且容易地检测包括蛋白质和与其特异性结合的抗体的本发明的试剂盒。被感染后,疫苗就可以广泛用于确认接种的成功与否。

著录项

  • 公开/公告号KR1021284530000B1

    专利类型

  • 公开/公告日2020-07-01

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020180034029

  • 发明设计人 이지후;이용직;김태윤;백영군;

    申请日2018-03-23

  • 分类号

  • 国家 KR

  • 入库时间 2022-08-21 10:55:26

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