VERFAHREN UND VORRICHTUNG ZUR LOKALISIERTEN INTRAVASKULAREN THERAPIE

摘要

A non-occlusive intravascular device for local application of a therapeutic agent to a selected segment of a lumenal wall of a blood vessel without applying radial force on the wall. The device comprises a radially expandable/collapsible flexible scaffold of an open-skeletal structure and a flexible outer surface capable of conforming to the lumenal wall without applying radial force thereon and a controllable mechanism for expanding and collapsing the scaffold. The therapeutic agent is loaded and carried on the outer surface of the scaffold. Also provided are a method and a system for delivering a therapeutic agent to a selected segment within a blood vessel.