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NOUVEAU DÉRIVÉ DE QUINOLINONE ET COMPOSITION PHARMACEUTIQUE POUR PRÉVENIR OU TRAITER UNE MALADIE ALLERGIQUE TELLE QUE L'ASTHME OU L'ATOPIE COMPRENANT CELUI-CI EN TANT QUE PRINCIPE ACTIF
NOUVEAU DÉRIVÉ DE QUINOLINONE ET COMPOSITION PHARMACEUTIQUE POUR PRÉVENIR OU TRAITER UNE MALADIE ALLERGIQUE TELLE QUE L'ASTHME OU L'ATOPIE COMPRENANT CELUI-CI EN TANT QUE PRINCIPE ACTIF
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摘要
The present invention relates to a novel quinolinone derivative compound that regulates intracellular signal transduction mediated by TSLP and IL-33 to exhibit efficacy in preventing or treating allergic diseases such as asthma or atopic dermatitis. The quinolinone derivative compound of the present invention can effectively suppress inflammatory responses of allergic diseases such as asthma or atopic dermatitis. The present invention also relates to a pharmaceutical composition including the quinolinone derivative compound. The pharmaceutical composition of the present invention can be used to fundamentally prevent or treat various allergic and asthmatic diseases.
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