PROCÉDÉ D'ÉVALUATION DU RISQUE DE RÉACTION D'HYPERSENSIBILITÉ À UN MÉDICAMENT INDUITE PAR LE SULFAMÉTHOXAZOLE ET/OU LE TRIMÉTHOPRIME

摘要

Provided is a method for evaluating the risk of drug hypersensitivity reaction induced by antibiotics sulfamethoxazole and/or trimethoprim. The drug hypersensitivity reaction comprises: maculopapular eruption, fixed drug eruption, Stevens-Johnson Syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms. A specific HLA genotype is associated with the drug hypersensitivity reaction induced by the antibiotics sulfamethoxazole and/or trimethoprim.