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COUCHES MINCES PROTÉIQUES MULTICOUCHES, PROCÉDÉS DE PRODUCTION, DISPOSITIFS DE DISTRIBUTION DE MÉDICAMENT ET IMPLANTS BIOMÉDICAUX UTILISANT LESDITES COUCHES MINCES
COUCHES MINCES PROTÉIQUES MULTICOUCHES, PROCÉDÉS DE PRODUCTION, DISPOSITIFS DE DISTRIBUTION DE MÉDICAMENT ET IMPLANTS BIOMÉDICAUX UTILISANT LESDITES COUCHES MINCES
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摘要
A multilayer protein film has a mass of greater than 0.5 μg/cm2 and consists essentially of protein. A drug delivery device comprises the multilayer protein film onto which a pharmaceutically active agent can be loaded. A biomedical implant comprises an implant substrate and the multilayer protein film on at least a portion of the implant substrate surface. A method of making a multilayer protein film having a mass of greater than 0.5 μg/cm2 comprises contacting a substrate with a protein solution at a temperature of from about 30° C. to about 95° C, wherein a multilayer protein film having a mass of greater than 0.5 μg/cm2 is formed on the substrate.
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