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PROMÉDICAMENT À BASE DE PHOSPHORE NOIR DOPÉ AU SÉLÉNIUM ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
PROMÉDICAMENT À BASE DE PHOSPHORE NOIR DOPÉ AU SÉLÉNIUM ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
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摘要
Disclosed is a selenium-doped black phosphorus prodrug comprising selenium-doped black phosphorus nanosheets and polyethylene glycol amine coating the surface of the selenium-doped black phosphorus nanosheets. The selenium-doped black phosphorus nanosheets comprise black phosphorus nanosheets and selenium elements doped in the black phosphorus nanosheets, with the selenium elements replacing positions of a portion of the phosphorus atoms in the black phosphorus crystal lattice. The selenium-doped black phosphorus prodrug is a controlled-release prodrug of selenium elements, which can realize the near-infrared light controlled-release of selenium elements, thereby controllably regulating selenium content in the human body, regulating human immunity, and preventing and treating cancers. Also provided is a method for preparing the selenium-doped black phosphorus prodrug.
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