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Long‐term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty

机译:硅胶掌指关节置换术多中心结局研究中对类风湿性关节炎患者的长期随访

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摘要

Objective Rheumatoid arthritis (RA) often results in deformities at the metacarpophalangeal (MCP) joints. Patients with severe deformities can be treated by silicone metacarpophalangeal joint arthroplasty (SMPA). The objective of the study is to prospectively compare long‐term outcomes for an SMPA surgical and a nonsurgical cohort of RA patients. Methods A total of 67 surgical and 95 nonsurgical patients with severe subluxation and/or ulnar drift of the fingers at the MCP joints were recruited from 2004–2008 in this multicenter prospective cohort study. Patients could elect to undergo SMPA or not. Outcomes included the Michigan Hand Outcomes Questionnaire (MHQ), Arthritis Impact Measurement Scales 2 (AIMS2), grip/pinch strength, Jebsen‐Taylor Test, ulnar deviation, extensor lag, and arc of motion measurements at the MCP joints. Results There was no significant difference in the mean age, race, education, and income at baseline between the 2 groups. Surgical subjects had worse MHQ function and functional measurements at baseline. At 3 years, the mean overall MHQ score and the MHQ function, activities of daily living, aesthetics, and satisfaction scores showed significant improvement in the surgical group compared to the nonsurgical group. Ulnar deviation, extensor lag, and arc of motion in the MCP and proximal interphalangeal joints also improved significantly in the surgical group. No improvement was seen in the mean AIMS2 scores and grip/pinch strength. Complications were minimal with a fracture rate of 9.5%. Conclusion RA patients with poor baseline functioning showed long‐term improvement in hand function and appearance following treatment with SMPA compared to nonsurgical controls.
机译:目的类风湿关节炎(RA)经常导致掌指(MCP)关节畸形。严重畸形的患者可以通过硅胶掌指关节置换术(SMPA)进行治疗。该研究的目的是前瞻性比较RA患者的SMPA手术组和非手术组的长期结局。方法从2004年至2008年,该多中心前瞻性队列研究共招募了67名外科手术患者和95名非手术患者,这些患者在MCP关节处出现严重的半脱位和/或尺骨移位。患者可以选择是否接受SMPA。结果包括密歇根州手结果调查表(MHQ),关节炎影响测量量表2(AIMS2),握力/捏力,捷成泰勒测试,尺骨偏斜,伸肌滞后和MCP关节活动度测量。结果两组的平均年龄,种族,教育程度和基线收入之间无显着差异。手术对象在基线时的MHQ功能和功能测量较差。与非手术组相比,手术组在3年时的平均总体MHQ评分和MHQ功能,日常生活活动,美学和满意度评分显示出显着改善。在手术组中,MCP和近端指间关节的尺骨偏斜,伸肌迟滞和运动弧度也明显改善。平均AIMS2得分和握力/捏力没有改善。并发症最少,骨折率为9.5%。结论与非手术对照组相比,基线功能较差的RA患者在接受SMPA治疗后表现出长期的手部功能和外观改善。

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