Final Report on the Developmental Toxicity of Sodium Fluoride (CAS No. 7681-49-4) in New Zealand White (NZW) Rabbits from Gestation Day 6 through Gestation Day 19 in Drinking Water. Laboratory Supplement

摘要

Contents: Introduction--Background, Uptake and Metabolism of Sodium Fluoride, General Toxicity of Sodium Fluoride, Reproductive and Developmental Toxicity of Sodium Fluoride, Study Rationale and Justification of Dose Levels; Test Chemical (Sodium Fluoride); Safety and Handling; Animals; Animal Husbandry; Dosage Formulation and Analysis; Treatment; Toxicologic and Teratologic Evaluation; Statistics; Storage of Records; Compliance with FDA and AAALAC Regulations; Personnel; Standard Operating Procedures; Study Records to be Maintained; References.