Daily Changes in Oxygen Saturation and Pulse Rate Associated with Particulate Air211 Pollution and Barometric Pressure

摘要

Epidemiology studies have linked fine particulate air pollution with211u001ecardiopulmonary mortality and morbidity. Although the underlying biological 211u001emechanisms remain largely unknown, resuls of several studies suggest that 211u001erespiratory and cardiovascular function may be an important factor. Potential 211u001epathways for observed cardiopulmonary mortality might include transient declines 211u001ein blood oxygenation and/or changes in pulse rate following exposures to 211u001eparticulate air pollution episodes. This study evaluated potential associations 211u001ebetween daily measures of respirable particulate air pollution (PM10) with pulse 211u001erate and oxygen saturation of the blood. Pulse rate and oxygen saturation (SpO2) 211u001eusing oximetry were measured daily in 90 elderly subjects living near air 211u001epollution monitors during the winter of 1995-96 in Utah Valley. Potential 211u001eassociations of oxygen saturation and pulse rate with barometric pressure were 211u001ealso evaluated. Small but statistically significant positive associations between 211u001eday-to-day changes in SpO2 and barometric pressure were observed. Pulse rate was 211u001einversely associated with barometric pressure. Exposure to particulate pollution 211u001ewas not significantly associated with SpO2 except for male participants 80 years 211u001eof age or older.