Laboratory Supplement for the Final Study Report of the Developmental Toxicity Evaluation for Methyleugenol (CAS No. 93-15-2) Administered by Gavage to Sprague-Dawley (CD(Trade Name)) Rats on Gestational Days 6 Through 19

摘要

;Contents: Appendix 4: Study Protocol and Amendments No. 1 through 7 Appendix 5: Summary of Dose Formulation Analyses and Chemistry Support Documents (Table A5-1. Summary of Dose Formulation Analyses; Dose Analysis Report, Methyleugenol, CHEM03542, May 21,1998; Dose Analysis Report, Methyleugenol, CHEM03549, June 5, 1998). Appendix 6: Supplemental Data Tables (Table A6-1. Laboratory Calendar; Table A6-2. Summary of Temperature and Humidity Ranges/Deviations). Appendix 7: Historical Data (Table A7-1. Historical Control Summary of Maternal Toxicity in CD Rats, Table A7-2. Historical Control Summary of Uterine Contents in CD Rats, Table A7-3. Historical Control Summary of Prevalence of Malformations and Variations in CD Rat Fetuses, Table A7-4. Historical Control Summary of Morphological Defects in CD Rat Fetuses); Appendix 8: Signature Page and QAU Statement.