Mixing and Processing of Complex Biological Fluids.

摘要

The primary deliverables for this research project have been the ability to predict the characteristics of the flow of complex biological fluids including viscoelastic fluids and blood, and the effect of microfluidic control on the makeup and molecular structure of biological fluids. For this project, we focused on two critical fluids that are biologically significant and that are of critical importance to DoD: DNA-laden fluids for early identification and diagnosis of pathogens, and blood for on-field reconstitution of whole blood from stabilized components. In addition to experimental investigations of complex fluid flows, computational and modeling capabilities have also been developed. The experimental results have been used to validate modeling tools at both Berkeley/LBL and at CFD Research Corporation. New capabilities for BioMEMS microelectricmicrofluidics design have been added to the commercial computational tools available from CFD Research Corporation as a result of this project.