The Influence of Clinically Undetectable Pulmonary Edema on Small Airway Closure in the Dog.

摘要

The relationship between elevated pulmonary extravascular water volume and small airway closure was examined. The slow accumulation of lung water was achieved by a combination of pulmonary venous hypertension and mild hemodilution. Trapped gas volume was measured by the helium equilibration technique. Clinically undetectable levels of pulmonary engorgement and edema were reproducibly associated with an increase in gas trapping.