Synthesis of the Laser Dyes, AC2F and AC3F,and Related Compounds.

摘要

The synthesis of the laser dye, AC2F,which is 2-oxo-6,9-dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-2H-pyrano(2,3-b)(1,8) naphthyridine,in nine steps from readily available starting materials is described. AC3F,which is the homologous 6,8,9-trimethyl compound,is made in six steps. Several related azacoumarins and azaquinolones,which fluoresce in the range 393-482nm in ethanol,have also been prepared. In addition, 2-oxo-6,9-dimethyl-8-phenyl-4-trifluoromethyl-6,7,8,9-tetrahydro-2H-pyrano(2,3-b)(1,8) naphthyridine has been made from 7-hydroxy-1,4-dimethyl-2-phenyl-1,2,3,4-tetrahydro-1,8-naphthyridine and sulfonated to furnish a water-soluble fluorescer (473nm). (Author)