Human Intravascular Immunoglobin Responses to Exercise-Heat and Hypohydration

摘要

The effects of prolonged treadmill exercise in the heat and hypohydration on changes in the intravascular mass of immunoglobins were examined. Five heat acclimated males attempted two Heat Stress Tests (HSTs). One HST was completed when subjects were euhydrated and the other HST when subjects were hypohydrated. The following observations were made concerning immunoglobin responses to hypohydration and exercise-heat stress: A) the changes in concentration of the measured immunoglobins were usually a direct reflection of changes in the plasma volume; B) hypohydration increased the intravascular mass (g) of the complement enzyme C3, but did not alter the intravascular mass of IgG, IgA, and IgM; and C) prolonged treadmill exercise in the heat, when either euhydrated or hypohydrated, did not alter the intravascular mass of IgG, IgA, IgM and C3. These data indicate that the intravascular mass of immunoglobins does not change during prolonged exercise in the heat, and that hypohydration results in a translocation of C3 to the intravascular space. Keywords: Dehydration. (aw)