Preliminary Assessment of the Oral Toxicity of 1,5-Diazido-3-Nitrazapentane, 2-and 6-Week Feeding Study, Male and Female Rats

摘要

A 2 and 6 week gavage feeding of DANPE caused testicular hypospermatogenesis inmale rats and pneumonitis in female rats. A NOAEL was not achieved in male rats but was achieved in female rats at the 56.00 mg/kg/day dose level.... 1,5-Diazido-3-Nitrazapentane (DANPE), Gavage, Testicular hypospermatogenesis, Insterstitual Inflammation No-observed-Adverse-Effect-Level(NOAEL), Feeding study.