EPR/Spin-Label Technique as an Analytical Tool for Determining the Resistance ofReactive Topical Skin Protectants (rTSPs) to the Breakthrough of Vesicant Agents

摘要

Ointment formulations of reactive topical skin protectants (rTSPs) or topicalskin protectants (TSPs) based on penluorinated polyether material (PFPE, i.e., fomblin RT.15) were prepared and spin labeled. Four N-oxyl-4-4'-dimethyloxazolidine derivatives of stearic acid, 5%NS, 7-NS, 12-NS, and l6-NS,