The EpiData Center (EDC) at the Navy and Marine Corps Public Health Center (NMCPHC) evaluated the Health Level 7 (HL7) formatted chemistry data source for its usefulness in health surveillance activities. This technical document provides a history of the HL7 chemistry database and its contents, explains the creation of chemistry/serology records, describes the pathway of data from healthcare provider to the EDC, provides detailed descriptions of all variables within the database, and assesses the databases strengths and limitations. Given an understanding of the strengths and limitations of the data, HL7 chemistry laboratory data have proven to be a valuable source of health information for surveillance purposes. The data allow the creation of a timeline of events corresponding to a specific disease occurrence. Furthermore, data are received in a timely fashion, allowing for near real-time surveillance of diseases.
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