Idiopathic interstitial pneumonias.

摘要

The idiopathic interstitial pneumonias (IIP) are a group of distinct clinicopathologic entities, "which are sufficiently different from one another to be designated as separate disease entities.The IIPs are an evolving group of diseases having undergone several classification schemes. Liebow and Carrington2 described the histologic classification for chronic interstitial pneumonia in 1969. Other classifications were proposed by Katzenstein3 and Miiller and Colby4 in 1997, in which lymphocytic interstitial pneumonia (LIP) and giant cell interstitial pneumonia were dropped. LIP was thought to be a lymphoproliferative disorder, which could progress to lymphoma. Many cases of giant cell interstitial pneumonia were subsequently recognized as hard metal pneumoconiosis from cobalt and tungsten carbide exposure. Additionally, the newly recognized interstitial pneumonias, such as respiratory bronchiolitis-associated interstitial lung disease (RB-ILD), bronchiolitis obliterans organizing pneumonia (BOOP), acute interstitial pneumonia (AIP), and nonspecific interstitial pneumonia (NSIP) were included in the classifications of the IIPs.