Photochemical preparation of 1,3,5,7-Tetracyanodadamantane and Its Conversion to 1,3,5,7-Tetrkis(aminomethyl)damantane

摘要

New adamantane derivatives1 and 2 that bear functionalized oen-carbon extensions at all four bridgehead positions have been prepared.Radical nucleophilic substitution(S_(RN1)reaction of 1,3,5,7-tetrabromoadamntane with cyanide produces 1,3,5,7-tetracyanoadamantane(1),which was reduced iwth borane reagents to 1,3,5,7-tetrakis(aminomethyl)adamantane(2).Improvements in the preparation of 1,3,5,7-tetrahaloadamantane(Halogen=Br,Cl,I)are also reported.