Comparison of joint destruction between standard- and low-dose etanercept in rheumatoid arthritis from the Prevention of Cartilage Destruction by Etanercept (PRECEPT) study

Tada Masahiro; Koike Tatsuya; Okano Tadashi; Sugioka Yuko; Wakitani Shigeyuki; Fukushima Kenzo; Sakawa Akira; Uehara Kazunori; Inui Kentaro; Nakamura Hiroaki

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Comparison of joint destruction between standard- and low-dose etanercept in rheumatoid arthritis from the Prevention of Cartilage Destruction by Etanercept (PRECEPT) study

机译：从通过Etanercept预防软骨破坏（PRECEPT）的研究比较类风湿关节炎中标准剂量和低剂量依那西普的关节破坏

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Objective. To evaluate the prevention of joint destruction and clinical efficacy of low-dose etanercept (ETN) (25 mg/week) compared with standard-dose ETN (50 mg/week) in RA.

机译：目的。为了评估RA的低剂量依那西普（ETN）（25 mg /周）与标准剂量ETN（50 mg /周）的关节破坏的预防和临床疗效。

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《Rheumatology》 |2012年第12期|共6页
作者
Tada Masahiro; Koike Tatsuya; Okano Tadashi; Sugioka Yuko; Wakitani Shigeyuki; Fukushima Kenzo; Sakawa Akira; Uehara Kazunori; Inui Kentaro; Nakamura Hiroaki;
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正文语种 eng
中图分类免疫性疾病;
关键词
rheumatoid arthritis; etanercept; radiographic outcome; safety; low-dose treatment; total modified Sharp score; efficacy; randomized controlled trial; radiographic progression; anti-tumour necrosis factor;

机译：类风湿关节炎;依那西普;影像学结果;安全性;小剂量治疗;改良Sharp评分总和;疗效;随机对照试验;影像学进展;抗肿瘤坏死因子;

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1. Comparison of joint destruction between standard- and low-dose etanercept in rheumatoid arthritis from the Prevention of Cartilage Destruction by Etanercept (PRECEPT) study [J] . Masahiro Tada1 Tatsuya Koike2 Tadashi Okano1 Yuko Sugioka1 Shigeyuki Wakitani1 Kenzo Fukushima3 Akira Sakawa4 Kazunori Uehara5 Kentaro Inui6 and Hiroaki Nakamura1 Rheumatology . 2012,第12期

机译：从通过Etanercept预防软骨破坏（PRECEPT）的研究比较类风湿关节炎中标准剂量和低剂量依那西普的关节破坏
2. Development and validation of a new radiographic scoring system to evaluate bone and cartilage destruction and healing of large joints with rheumatoid arthritis: ARASHI (Assessment of rheumatoid arthritis by scoring of large joint destruction and healing in radiographic imaging) study [J] . KanekoA., MatsushitaI., KanbeK., Modern rheumatology . 2013,第6期

机译：开发和验证一种新的放射学评分系统，以评估类风湿关节炎大关节的骨骼和软骨的破坏和愈合：ARASHI（通过对影像学影像中的大关节破坏和愈合进行评分来评估类风湿性关节炎）研究
3. Assessing joint destruction in the knees of patients with rheumatoid arthritis by using a semi-automated software for magnetic resonance imaging: therapeutic effect of methotrexate plus etanercept compared with methotrexate monotherapy [J] . Oka Hiroyuki, Kadono Yuho, Ohashi Satoru, Modern rheumatology . 2018,第2期

机译：利用半自动软件对磁共振成像进行了类风湿性关节炎膝关节炎的关节破坏：与甲氨蝶呤单药治疗相比，甲氨蝶呤加乙酸乙酯的治疗效果
4. ETANERCEPT IN THE TREATMENT OF AA AMYLOIDOSfS IN JUVENILE RHEUMATOID ARTHRITIS-PRELIMINARY EXPERIENCE [C] . H. Michels, R. Hafner, R.P. Link International Symposium on Amyloidosis . 2005

机译：依赖替辛醚治疗少年类风湿性关节炎中AA淀粉样液 - 初步体验
5. Comparison of Individually-Adjusted Heparin Versus Ultra Low-Dose Aspirin for Prevention of Thromboemboli in Immune-Mediated Hemolytic Anemia in Dogs And The Safety of Ultrasound-Guided Fine Needle Aspiration of the Feline Pancreas: A Case-Control Study. [D] . Crain, Sarah Kathleen. 2014

机译：个体调节肝素与超低剂量阿司匹林预防犬免疫介导的溶血性贫血中血栓栓塞的效果比较以及超声引导的猫胰腺细针抽吸安全性：病例对照研究。
6. Switch from reference etanercept to SDZ ETN an etanercept biosimilar does not impact efficacy safety and immunogenicity of etanercept in patients with moderate-to-severe rheumatoid arthritis: 48-week results from the phase III randomized double-blind EQUIRA study [O] . Janusz Jaworski, Marco Matucci-Cerinic, Hendrik Schulze-Koops, 2019

机译：从参考依那西普转向依那西普生物仿制药SDZ ETN不会影响依那西普在中度至重度类风湿关节炎患者中的功效安全性和免疫原性：III期随机双盲EQUIRA研究的48周结果
7. Comparison of injection site reactions between the etanercept biosimilar SB4 and the reference etanercept in patients with rheumatoid arthritis from a Phase III study [O] . Girolomoni, G, Feldman, SR, Emery, P, 2017

机译：比较III期研究中依那西普生物仿制药sB4与参考依那西普在类风湿性关节炎患者中的注射部位反应

Comparison of joint destruction between standard- and low-dose etanercept in rheumatoid arthritis from the Prevention of Cartilage Destruction by Etanercept (PRECEPT) study

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