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Role of MDCT in Detection and Characterisation of Focal Liver Lesions

机译:MDCT在局灶性肝病变检测和表征中的作用

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Multiphasic Computed Tomography (CT) has become the primary imaging modality for detection and characterisation of focal liver lesions. CT has assumed primary role in evaluating hepatic masses.Aim: To assess the imaging features of focal liver lesions on Multidetector Computed Tomography (MDCT) and its comparative evaluation with histopathological results.Materials and Methods: This cross-sectional study was conducted in the Department of Radiodiagnosis in a tertiary care hospital for a period of 18 months. Adult patients of age group 20-60 years with focal hepatic lesions on abdominal imaging (USG), all patients presenting with deranged liver function or known cases of liver mass lesions were included in the study and Quadriphasic Contrast Enhanced Computed Tomography (CECT) scan was done for them followed by biopsy. All the values for the arterial phase, venous phase, portal phase and delayed phase were recorded and analysed along with the histopathological and biochemical analysis report.Results: As detected by MDCT, out of 84 focal liver lesions, benign focal liver lesions were 72(85.7) and malignant lesions were 12 (14.3). The diagnostic accuracy (efficiency) of MDCT was found to be 90.5 with predicted value (95 CI: 84.20-96.75). For the hepatocellular carcinoma cases, highly significant agreement (pConclusion: This study indicates MDCT to be highly sensitive in classifying the hepatic lesions into clinically relevant categories, making diagnosis and evaluation of lesion. It opens up new possibilities of early detection of liver lesions and its management.
机译:多相计算机断层扫描 (CT) 已成为检测和表征局灶性肝脏病变的主要成像方式。CT 在评估肝脏肿块方面发挥了主要作用。目的:评估多排计算机断层扫描(MDCT)局灶性肝病变的影像学特征及其与组织病理学结果的比较评估。材料和方法:这项横断面研究在三级医院的放射诊断科进行,为期 18 个月。20-60 岁年龄组的腹部影像学检查 (USG) 显示局灶性肝病变的成年患者、所有出现肝功能紊乱或已知肝脏占位性病变病例的患者均被纳入研究,并对他们进行四相造影增强计算机断层扫描 (CECT) 扫描,然后进行活检。记录动脉期、静脉期、门静脉期和延迟期的所有值,并结合组织病理学和生化分析报告进行分析。结果:MDCT检测结果显示,84例局灶性肝病变中,良性局灶性肝病灶72例(85.7%),恶性肝病灶12例(14.3%)。MDCT的诊断准确率(效率)为90.5%,预测值为95%CI:84.20-96.75%。对于肝细胞癌病例,MDCT 和活检技术之间存在高度显着的一致性 (p<0.001)。恶性病变的总体敏感性、特异性、PPV、NPV和诊断准确率为83。分别为3%、97.2%、83.3%、97.2%和95.2%。结论:MDCT对肝脏病变的临床相关分类具有高度敏感性,对病变进行诊断和评估。它为早期发现肝脏病变及其管理开辟了新的可能性。

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